도청신도시 예천 136 : 개에서심방중격...개에서Tiletiamine...

---

  개에서 심방중격결손의 증례(개에서 심방중격 缺損의 證例 =Atrial Septal Defect in Dogs) [學術저널] : 호명면 담암리 담바우 출신인 장광호(張洸鎬, 大昌高 卒業, 慶北大 敎授) 등(엄기동 오태호 이영원 윤정희 정주현 장동우)의 논문으로, 한국임상수의학회(URL //www.ksvc.or.kr)에서 2002년에 발행한 <한국임상수의학회지(韓國臨床獸醫學會誌)> Vol.19 No.1 110-113쪽(4쪽 分量)에 수록되어 있다. 제어번호 19743267, KDC 528이다. [초록] : An atrial septal defect (ASD) is a congenital hole in the atrial septum that allows flow between the two atria. Small ASDs are usually well-tolerated defects and do not result in significant clinical abnormalities. In large ASDs or in the presence of other cardiac defects, clinically significancy is increased. Atrial septal defects in 2 Dogs with cardiac and respiratory signs were diagnosed at seoul animal medical center. In ascultation, systolic murmur and the splitting of second heart sound were heard at pulmonary or tricuspid valve region. In radiograph, right-sided cardiomegaly, pulmonary artery dilation, increased pulmonary vasculature makings, and pleural effusion or pulmonary edema signs were observed. In echocardiography, the region, location and size of septal defect was identified. Also, the direction and degree of shunt was measured. These dogs were treated with medicine for cardiac failure. One dog is well-tolerated, the other dog died.(keris 2003 2005 2006)

  개에서 외이도내 발생한 폴립성 골종 증례(개에서 외이도내 發生한 폴립性 骨腫 證例 =A Case of External Ear Osteoma as a Polyp in Dog) [學術저널] : 호명면 담암리 담바우 출신인 장광호(張洸鎬, 大昌高 卒業, 慶北大 敎授) 등(Eom, Ki-dong Oh, Tae-ho Park, Soo-won)의 논문으로, 한국임상수의학회(URL //www.ksvc.or.kr)에서 2003년에 발행한 <한국임상수의학회지(韓國臨床獸醫學會誌)> Vol.20 No.3 396-398쪽(3쪽 分量)에 수록되어 있다. 언어 English, 제어번호 40037853, KDC 528이다. [초록] : 체중 3.8㎏인 두 살 된 말티즈 암컷이 왼쪽 귀에서 핑크색 분비물과 통증을 호소하여 내원하였다. 수평외이도내 폴립이 확인되었다. 조직병리 검사 결과 폴립은 골종으로 확진되어 총이도박리술로 제거하였다. 그러나 수술 3개월후 부종성 피부병변을 동반한 골종이 재발하였다. 폴립 기저부와 부착된 주변조직의 철저한 제거가 골종 재발을 방지 할 수 있다는 결론을 얻었다. =A 2 year-old, 3.8 kg, intact female Maltese was presented with unilateral pain and reddish discharge from the left ear caused by a polyp in the horizontal ear canal. The polyp was diagnosed as osteoma histopathologically and removed through total ear canal ablation. Three months after surgery, osteoma was recurred and broken out of edematous skin lesion. It was considered that an inappropriate surgical removal of the tissue which attached base boarder of the polyp would be cause of the recurrence of the osteoma. [목차] : Abstract/ Introduction/ Case/ Discussion/ References/ 요약(keris 2005 2006)

  개에서 전십자 인대 단열의 초음파적 평가(개에서 전십자 靭帶 斷裂의 超音波的 評價 =Ultrasonographic Evaluation of Surgically Induced Cranial Cruciate Ligament Rupture in the Dog) [學術저널] : 호명면 담암리 담바우 출신인 장광호(張洸鎬, 大昌高 卒業, 慶北大 敎授) 등(성윤상 엄기동)의 논문으로, 한국임상수의학회(URL //www.ksvc.or.kr)에서 2003년에 발행한 <한국임상수의학회지(韓國臨床獸醫學會誌)> Vol.20 No.2 229-232쪽(4쪽 分量)에 수록되어 있다. 제어번호 40037823, KDC 528이다. [초록] : Ultrasonographic examination of the stifle joint four clinically and radiographically normal adult dogs was performed before and after inducing the cranial cruciate ligament (CKL) rupture of the bilateral stifle surgically. At pre- or post-surgery, the hyperechoic patella ligament and the echogenic infrapatella fat interfered the visualization of the CKL by the plain scanning method. However when the stifle joint was imaged by the scanning method injecting normal saline within the joint capsule, the hyperechogenic ligament was visualized by the separation of the infrapatella fat and the CKL and the contrast effect of anechoic saline. When the stifle joint was imaged by the real time scanning method after the induction of the surgical rupture, fluttering of the ligament and anechoic area between the bone and the CrCL was identified due to the lack of tonicity and continuity of the ligament. Enlargement of the ligament because of its increased diameter as well as fluttering of the CKL and the increased joint space s thickness was visualized. Consequently, confirming fluttering of the CKL, increased ligament diameter and anechoic region between the CrCL and the bone, ultrasonographic examination is a valuable diagnostic tool as well as cranial drawer test and radiographic examination.(keris 2005 2006)

  개에서 전층피부 창상에 대한 Hydrocolloid(Duoderm^(?))과 Hydrogel(Nu-Gel^(?))의 치료 효과 비교 연구(개에서 전층皮膚 창상에 對한 Hydrocolloid(Duoderm^(?))과 Hydrogel(Nu-Gel^(?))의 治療 效果 比較 硏究 =A Comparative Study of Hydrocolloid(Duoderm^(?)) and Hydrogel(Nu-Gel^(?)) Occlusive Dressing Materials in the Treatment of Full-Thickness Skin Wound in Dogs) [學術저널] : 호명면 담암리 담바우 출신인 장광호(張洸鎬, 大昌高 卒業, 慶北大 敎授) 등(Kwon, Young-Sam Rhee, Jung-Woo)의 논문으로, 한국임상수의학회(URL //www.ksvc.or.kr)에서 2003년에 발행한 <한국임상수의학회지(韓國臨床獸醫學會誌)> Vol.20 No.3 294-301쪽(8쪽 分量)에 수록되어 있다. 언어 English, 제어번호 40037836, KDC 528이다. [초록] : 개의 전층피부 창상에서 삼출물의 정도와 창상수축, 상피화, 그리고 치유에 대해 hydrocolloid(Duoderm^(?), HC)과 hydrogel(Nu-Gel^(?), HG) occlusive dressing materials의 효과를 비교하였다. 3쌍의 정사각형 전층피부 창상을 2×2㎝의 크기로 12마리 개의 몸통 등외측 면에(6개의 창상/한 마리) 만들었다. HC와 HG, 생리 식염수(대조창)를 무작위로 배분한 2개의 창상에 각각 적용하였다. 창상의 육안적 소견과 병리조직학적 소견을 4주 동안 평가하였다. 창상유발 7일 후, 비교 그룹 간의 평균 창상수축 정도, 평균 상피화율, 평균 창상 치유율에 유의성있는 변화가 관찰되지 않았다. 창상 유발 14일(p＜0.01)과 21일(p＜0.05) 후, HG 처치창의 평균 상피화율이 HC 처치창의 평균 상피화율과 대조창의 상피화율보다 유의적으로 더 높게 나타났다. 창상 유발 21일 후((p＜0.05), HG 처치창의 창상 수축율이 HC 처치창의 평균 창상 수축율과 대조창의 평균 창상 수축율보다 유의적으로 더 높게 나타났다. 창상 유발 21일 후 (p＜0.02), HG 처치창의 창상 치유율이 HC 처치창의 평균 창상 치유율과 대조창의 평균 창상 치유율보다 유의적으로 더 높게 나타났다. 창상 유발 1, 4, 7일 후, HC 처치창과 대조창의 피하에 다형핵 백혈구의 심한 침착이 관찰되었고, HG 처치창의 피하에 중등도의 다형핵 백혈구의 침착이 관찰되었으나, HG 처치창, HC 처치창, 대조창 간의 어떠한 유의적인 변화도 발견되지 않았다. 창상 유발 14일 후, HG 처치창에서 상피성 세포가 유의적으로 표면 위로 자라났고, 부종은 창상 밑 조직까지 감소하였으며, 육아조직은 교원질 섬유로 대체되었다.

  창상 유발 21일 후, 다른 창상에 비해, HG 처치창은 유의적으로 창상 표면이 거의 재생성 상피로 덮였으며, 육아조직은 창상 유발 14일 후와 비교해서 유의적으로 교원질 섬유로 대체되었다. 위의 모든 결과에서 보듯이, 개에서 전층피부 창상의 처치 시 HG의 사용은 HC와 생리 식염수에 비해 창상치유 복구기의 치유 속도를 촉진하는 것으로 사료된다. =This study was performed to compare the effects of hydrocolloid(Duoderm^(?), HC in this study) and hydrogel (Nu-Gel^(?), HG in this study) occlusive dressing materials on degree of exudate, wound contraction, epithelialization, and healing of full-thickness skin wounds in dogs. Three wounds measuring 2x2 cm in size were created bilaterally(6 wounds/ dog) on the dorsolateral aspect of the trunk of 12 dogs. In each dog, the wounds were treated with HC, HG, and normal saline, respectively. For a 4 week period, the wounds were evaluated gross aspects and histopathological aspects. There were no statistically significant differences between treatment groups in percentage of wound contraction, percentage of epithelialization, and percentage of wound total healing during the first week. Significant differences were first detected on day 14. On day 14(P<0.01) and 21(P<0.05), mean percentage of epithelialization of HG-treated wound was significantly greater than those in HC- and normal saline-treated wound. Mean percentage of wound contraction of HGtreated wound was significantly greater than that in HC- and control wounds on day 21(P<0.05). On day 21, mean percentage of wound healing of HG-treated wound was significantly greater than that in HC- and control wounds(P<0.02). On day 1, 4, and 7 after wound creation, although severe infiltration of PMN (polymorphonuclear leukocyte) cells in HC- and control wounds were observed in the subcutis and moderate infiltration of PMN cells in HG-treated wound were observed in the subcutis, we did not detect significant differences. On day 14 after wounding creation, in the wounds treated with HG dressing, epithelial cells were found over the surface, and edema further decreased in the tissue under the wounds, and the granulation tissue was replaced with collagen fibers. On day 21 after wound creation, in HG-treated wound compared with other experimental material-treated wounds, regenerated epidermis covered most of the wound surface, and the granulation tissue was more replaced with collagen fibers than that on day 14. Overall results indicated that the use of hydrogel dressing materials(Nu-Gel^(?)) as hydrocolloid dressing (Duoderm^(?)) materials and normal saline treatment on full-thickness skin wounds in dogs increased the rate of healing at repair stage. [목차] : Abstract/ Introduction/ Materials and Methods/ Results/ Discussion/ References/ 요약(keris 2005 2006)

  개에서 Conjugated Linoleic Acid와 Carprofen이 실험적 골관절염 초기 진행에 미치는 효능(개에서 Conjugated Linoleic Acid와 Carprofen이 實驗的 骨關節厭 初期 進行에 미치는 效能 =The Efficacy of Conjugated Linoleic Acid and Carprofen in Progression of Early Stage of Experimentally Induced Osteoarthritis in Dogs) [學術저널] : 호명면 담암리 담바우 출신인 장광호(張洸鎬, 大昌高 卒業, 慶北大 敎授) 등(Park, Se-il Bae, Jae-sung Kwon, Young-sam Jang, Hwan-soo Li, Wen-xue Lim, Jae-hyun Eom, Ki-dong Kim, Jung-eun)의 논문으로, 한국임상수의학회(URL //www.ksvc.or.kr)에서 2003년에 발행한 <한국임상수의학회지(韓國臨床獸醫學會誌)> Vol.20 No.3 278-285쪽(8쪽 分量)에 수록되어 있다. 언어 English, KDC 528, 제어번호 40037834이다. [초록] : 개에서 실험적으로 앞쪽 십자인대 중간부를 절단한 다음 초기 병변을 관찰하고 그 초기 병변에 대한 conjugated linoleic acid (CLA), carprofen 그리고 두 약물의 병용에 따른 효과를 비교하고자 본 실험이 수행되었다.

  실험견은 앞쪽 십자인대를 파열한 CLA 처치군, Carprofen 처치군, CLA와 Carprofen 병용처치군 그리고 양성대조군과 파열하지 않은 정상견으로 구성된 음성대조군으로 총 5개군으로 분류하고 각 군에 5두씩 배치하였다. 실험견의 무릎관절 외측 피부를 절개하고 관절낭 외측을 절개한 다음 앞쪽 십자인대 중간부로 판단되는 부위를 절단하였다. Carprofen과 CLA는 수술 후 4주부터 4주 동안 경구 투여하였다. 술후 8주 후에 육안적, 조직학적 평가를 실시하였다. 조직학적 검사로는 hematoxylin and eosin 염색, standard toluidine blue, PAS 그리고 Masson trichrome 염색법을 이용하였으며 혈액학적, 그리고 방사선학적 검사를 실시하였다. 조직학적 검사와 혈액학적 검사에서 유의적인 변화는 나타나지 않았다. 방사선 검사에서는 앞쪽 십자인대 파열에 따른 대퇴골과 경골의 정렬이상과 부종이 모든 군에서 나타났으며 육안적 검사에서는 대부분 실험견의 대퇴 연골 표면상이 엷은 황색을 보였다. 이상의 결과를 통하여 실험적으로 유발된 개의 앞쪽 십자인대 파열에 대해 CLA, carprofen 그리고 이들의 합제는 초기 변화상에서 뚜렷한 변화를 나타내지 않았다. =This study was performed to compare early stage changes following the administrations of Conjugated Linoleic Acid (CLA), Carprofen and their combinations in the experimental canine cranial cruciate ligament rupture. Twenty five mongrel dogs were divided into five groups; Groups 1, 2, and 3 received a sectioning the cranial cruciate ligament (CCL) of the right stifle joint, and were administered CLA (250 mg/kg/day/orally), carprofen (4.4 mg/kg/day/orally), and their combinations for 4 weeks beginning 4 weeks postsurgery, respectively. Group 4 received sectioning CCL and no treatment. Group 5 was composed of unoperated normal dogs. The macroscopic observation of cartilage erosions on both the condyles and plateaus were evaluated, and the severity of the cartilage lesions and synovial inflammation was examined histologically at eight weeks after surgery. Histological examinations including hematoxylin and eosin stain, standard toluidine blue method, PAS technique and Masson trichrome technique, hematologic and radiographic evaluation were performed after experimental surgery. Slight yellowish discoloration of the surface was found in some of the experimental dogs. However macroscopic findings showed no significant differences among the groups. In radiographic findings, cranial displacement of the proximal tibia relative to the femoral condyles in all groups was observed but no significant differences among the groups was seen. This study showed that oral administration of CLA, carprofen and their combinations revealed no early stage change in the canine stifle joint following experimental rupture of the cranial cruciate ligament. [목차] : Abstract/ Introduction/ Materials and Methods/ Results/ Discussion/ References/ 요약(keris 2005 2006)

  개에서 Tiletamine-Zolazepam의 연속투여가 생체에 미치는 영향(개에서 Tiletamine-Zolazepam의 連續投與가 生體에 미치는 影響 =Effects of continuous administration of Tiletamine - zolazepam in dogs) [學術저널] : 호명면 담암리 담바우 출신인 장광호(張洸鎬, 大昌高 卒業, 慶北大 敎授) 등(박명호 서강문)의 논문으로, 대한수의학회(URL //www.ksvs.or.kr/)에서 1997년에 발행한 <대한수의학회지(大韓獸醫學會誌)> Vol.37 No.2 457-462쪽(6쪽 分量)에 수록되어 있다. 제어번호 3115661, KDC 528이다. [초록] : The effects of continuous administration of tiletamine-zolazepam(T-Z) on the blood, liver and kidney of dogs were evaluated. The drug was repeatedly administered into ten mongrel dogs intramuscularly at dose of 10㎎/㎏ for every seven days./ Hematology(PCV, WBC, RBC, TP, Fibrinogen) and serum chemistry(ALT, AST, BUN, Creatinine) were monitored for 14 days postinjection. No significant changes in PCV values, total RBC counts and plasma total protein values was found. Total WBC counts and fibrinogen values were significantly increased from 2 days to 7 days postinjection. There was no significant change in ALT, AST, BUN and creatinine levels. All animals were euthanized and necropsied at 14 days postinjection. No gross lesion and pathologic lesion was found on liver and kidney in necropsy finding.(keris 2003 2005 2006)